New insights to ellagitannin-protein interaction by ITC

Ellagitannins with glucopyranose cores have higher affinities to proteins than acyclic ellagitannins by isothermal titration calorimetry Recently, we published a paper looking at the ellagitannin-protein interactions and their thermodynamics by isothermal titration calorimetry (ITC): Karonen M, Oraviita M, Mueller-Harvey I, Salminen J-P, Green Rebecca J. 2019. Ellagitannins with glucopyranose cores have higher affinities to proteins […]

New results on tannin-protein interactions

Structural features of hydrolysable tannins reveal their capacity to precipitate a model protein Our long term efforts at the Natural Chemistry Research Group regarding structure-activity studies of hydrolysable tannins (HTs) have resulted in a new scientific paper by Engström et al. (2019) reporting the ability of 32 purified and characterized HTs to form insoluble complexes with […]

New tannin purification tool

The best NCRG paper of 2018: Leppä et al. Journal of Chromatography A 1576:67–79.  We at the Natural Chemistry Research Group had an internal vote for our best paper published in 2018. Milla’s paper reporting the developments in the chromatographic purification of proanthocyanidins came out as a clear winner. Congrats Milla! This was actually a perfect […]

Two papers by NCRG made into the top 4% of JAFC

Advances in Polyphenol Research: A Journal of Agricultural and Food Chemistry Virtual Issue Scientists have investigated polyphenols since at least the start of the 19th century, and these compounds continue to be the subject of intense activity, with some 500 papers published in just the Journal of Agricultural and Food Chemistry (JAFC) between January 2016 and July […]

Want to have an MSc in Natural Compound Chemistry?

Positions are now open in our Master’s Degree Programme, where you can choose between three disciplines belonging to the field of Medicinal and Radiopharmaceutical Chemistry Our programme provides you with strong knowledge on one or more of the following topics: design and synthesis of new drugs, radiolabelling and enhanced targeting of drugs, or screening, isolation […]

In Memoriam, Dick Hemingway 1939-2018

Outstanding tannin chemist and the founding father of the Tannin Conferences, Richard (Dick) William Hemingway has passed away After a long and rich life as a phytochemist, mentor, and loving husband and father, Dick Hemingway passed away in Pineville, Louisiana where he had lived and worked for many years. He will be missed by his family, […]

The most extensive Eucalyptus screening results revealed

Group-specific UPLC-MS/MS analyses of eight groups of polyphenols of 628 eucalypts from the genera Eucalyptus, Angophora and Corymbia revealed wide presence of high concentrations of polyphenols, particularly ellagitannins Marsh et al. (2017) was the first paper resulting of our collaborative efforts with Bill Foley’s group to better understand the role of eucalypt polyphenol chemistry in […]

Chemistry shows how to eat a rainforest

Recent multidisciplinary project combined evolutionary history and plant chemistry to understand and predict the occurrence of herbivorous insects across rainforest plants. This study was published in the prestigious journal, Proceedings of the Royal Society B. Papua New Guinea is one of the few places on earth where one can find large areas of still untouched […]

New tools for bioactive oligomeric ellagitannins

MSc Nicolas Baert from the Natural Chemistry Research Group (http://naturalchemistry.utu.fi) defended his doctoral thesis on August 18. The excellent doctoral training Nicolas enjoyed during the LegumePlus project has already paid off, since Nico travelled to Turku from the Cornell University, New York, where he holds his new post-doc position. It is perhaps a matter of […]

NCRG tannin analyses expand to Australia

There are more than 600 species of Eucalyptus in Australia and only little is known of their exact composition and content of ellagitannins, galloyl glucoses, gallotannins, procyanidins and prodelphinidins. Such knowledge would be crucial to understand and make improvements to Eucalyptus-herbivore interactions. Eucalyptus–koala interactions Koalas are unique to Australia and perhaps the best known and […]